Review paper on new functionalities for hydroxyapatite

Dr. Anna Díez-Escudero, Dr. Montserrat Español and Prof. Maria-Pau Ginebra have just published the review paper "High-aspect-ratio nanostructured hydroxyapatite: towards new functionalities for a classical material", which is part of the themed collection: 2023 Chemical Science Perspective & Review Collection. 

The article explores the advancements in the field of hydroxyapatite, a classical biomaterial commonly used in bone tissue engineering. The focus of the study is on high-aspect-ratio nanostructured hydroxyapatite, where the material is engineered at the nanoscale to possess high aspect ratio structures. This nanostructuring imparts novel functionalities to hydroxyapatite, enhancing its potential applications.

It delves into the different synthesis methods employed to achieve high-aspect-ratio nanostructures, highlighting their significance in promoting cellular adhesion, proliferation, and overall tissue integration. The researchers discuss the potential benefits of these nanostructures in improving the mechanical properties and bioactivity of hydroxyapatite, crucial factors for its success in biomedical applications, rendered by the nanoscale interactions with proteins and cellular components. Additionally, the article describes new applications of these particular nanostructures in fields beyond bioengineering, such as catalysis, energy or sustainability.

Overall, the research underscores the transformative potential of high-aspect-ratio nanostructured hydroxyapatite, paving the way for enhanced biomaterials with improved performance in regenerative medicine and other biomedical applications.

The paper is published under an Open Access license, so you can access it for free by following this link.